For Business Use Only. Does Not Ship to Residential Addresses. For use inside an Analyzer, Sold Separately.
Beckman Coulter Access Thyroglobulin Antibody II Reagent, 100 Determinations, 2 x 50 tests
Easily reorder reagents and American-made parts.
Enjoy the fair price promise.
Take pressure off your budget (and yourself)
Product Code: A32898
Manufacturer: Beckman Coulter
Shipping Weight: 10.00lbs (4.54kg)
Specifications
Brand: Access®
Manufacturer: Beckman Coulter
Country of Origin: United States
Application: Reagent
For Use With: For use with Access Immunoassay Systems
Number of Tests: 100 Tests
Test Name: Anti-Thyroglobulin 2
Test Type: Antibody Test
Intended Use
The Access Thyroglobulin Antibody II (TgAb) assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of thyroglobulin antibody levels in human serum and plasma using the Access Immunoassay Systems. The measurement of thyroid autoantibodies may aid in the diagnosis of Hashimoto's disease, nontoxic goiter, and Graves' disease.
Summary and Explanation
Thyroglobulin is produced by the thyroid gland. It is a water soluble glycoprotein of approximately 660,000 Daltons. It is a major component of the thyroid follicular colloid and is present in small amounts in serum. The principal role of thyroglobulin is the storage and synthesis of thyroid hormones. The thyroid hormones 3, 5, 3', 5', - tetraiodothyronine (thyroxine, T4) and 3, 5, 3', -triiodothyronine (T3) are synthesized from thyroglobulin.
Thyroglobulin autoantibodies (TgAb) are often present in patients with autoimmune thyroid disease. Approximately 10% of healthy individuals have TgAb at measurable levels. TgAb can be detected in 30% of patients with Graves' disease and in 85% of patients with Hashimoto's thyroiditis. However, elevated levels of autoantibodies to thyroid peroxidase (TPO autoantibodies) occur more frequently than high TgAb levels in these diseases.
Sensitive TgAb methods are needed to identify patient sera that contain thyroglobulin autoantibodies that may interfere with serum thyroglobulin measurements.
