Immunalysis 302UR-0100 Oxycodone Reagent, 100mL

Immunalysis 302UR-0100 Oxycodone Reagent, 100mL

Oxycodone is a semi-synthetic narcotic analgesic generally prescribed for the relief of moderate to severe pain. Its potency is approximately equivalent to morphine. Oxycodone is available as a single compound, but is often combined with other analgesics like acetaminophen or aspirin. In the last decade, it has become the leading opioid in the United States, where the medical use of opioids increased 400% from 1996 through 2000. 1

Administration: Oral, intramuscular, and intravenous injections.

Elimination: Oxycodone and its metabolites are excreted primarily via the kidney. Approximately 8%-14% of the dose is excreted as free oxycodone, up to 50% as conjugated oxycodone, 0% as free oxymorphone, 14% as conjugated oxymorphone, whereas both free and conjugated noroxycodone have been found in the urine but not quantified.2 Elimination half-life is independent of dose and route of administration. The elimination half-life of controlled-release oxycodone is 4,5 h compared to 3,2 h for immediaterelease oxycodone.1

Abuse Potential: Oxycodone has high potential for physical and psychological dependence. It can be abused in a manner similar to other opioid agonists, legal or illicit. It is generally abused by crushing, chewing, snorting, smoking, or injection. These practices pose a significant risk to the abuser that could result in overdose or death.3