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Olympus OSR6004 Beckman Coulter 3P ALP R1 4X12ML R2 4X12ML

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    Product Code: OSR6004

    Shipping Weight: 10.00lbs (4.54kg)

    Specifications

    Manufacturer: Beckman Coulter
    Country of Origin: Ireland
    Application: Reagent
    Number of Tests: 4 X 310 Tests
    Storage Requirements: Requires Refrigeration
    Test Name: Alkaline Phosphatase (ALP)
    Test Type: General Chemistry
    UNSPSC Code: 41116004
    Volume: 4 X 12 mL, 4X 12 mL


    Intended Use

    System reagent for the quantitative determination of Alkaline Phosphatase activity in human serum and plasma on Beckman Coulter AU analyzers.

    OSR6504 for use on the AU680, AU2700 and AU5400 systems only.

    OSR6604 for use on the AU5800, AU2700 and AU5400 systems only


    About Alkaline Phosphatase 

    Measurements of serum alkaline phosphatase (ALP) (EC 3.1.3.1) are used in the diagnosis of hepatobiliary disorders and bone disease associated with increased osteoblastic activity. Certain conditions such as Hodgkin’s Disease, congestive heart failure and ulcerative colitis will produce moderate elevation in alkaline phosphatase levels. Non-pathologic elevations can be observed in third trimester of pregnancy.


    Methodology

    This ALP procedure is based on the method developed by Bowers and McComb2 and has been formulated as recommended by the AACC and IFCC.

    Alkaline phosphatase activity is determined by measuring the rate of conversion of p-nitro-phenylphosphate (pNPP) in the presence of 2-amino-2-methyl-1-propanol (AMP) at pH 10.4.

     

    The rate of change in absorbance due to the formation of pNP is measured bichromatically at 410/480 nm and is directly proportional to the ALP activity in the sample. 


    Additional description

      Alkaline Phosphatase - Safety Data Sheet 
      Alkaline PhosphataseInstructions for Use