For Business Use Only. Does Not Ship to Residential Addresses. For use inside an Analyzer, Sold Separately.
Specifications
Manufacturer: Beckman Coulter
Country of Origin: Ireland
Application: Reagent
Number of Tests: 4 X 240 Tests
Test Name: Unsaturated Iron Binding Capacity (UIBC)
Test Type: General Chemistry
UNSPSC Code: 41116004
Volume: 4 X 27 mL, 4 X 3 mL, 4 X 6 mL, 4 X 2 mL
Intended Use
System reagent for the quantitative determination of Unsaturated Iron Binding Capacity (UIBC) in human serum and plasma on Beckman Coulter AU analyzers.
About UIBC (Unsaturated Iron Binding Capacity) Reagent
Iron (non-heme) measurements are used in the diagnosis and treatment of diseases such as iron deficiency anemia, hemochromatosis (a disease associated with widespread deposit in the tissues of two iron-containing pigments, hemosiderin and hemofuscin, and characterized by pigmentation of the skin), and chronic renal disease. Transferrin is the major iron carrying protein in the serum. Serum iron concentration connotes the Fe (III) bound to serum transferrin and does not include the iron contained in serum as free hemoglobin. Because normally only about one third of the iron binding sites of transferrin are occupied by Fe (III), serum transferrin has considerable reserve Iron Binding Capacity. This is called the serum Unsaturated Iron Binding Capacity (UIBC).
Methodology
In this UIBC procedure intended for use on the Beckman Coulter automated AU analyzers, ferrous-Iron (Fe2+) at alkaline pH, added to serum, binds specifically with transferrin at unsaturated iron binding sites. Remaining unbound ferrous iron reacts with the Nitroso-PSAP [2-Nitroso-5-(N-propyl-Nsulfopropylamino)phenol] to form an intense green complex. The difference between the resulting change in the measured absorbance and the absorbance from the total amount added to serum is equivalent to the quantity bound to transferrin. This is the Unsaturated Iron Binding Capacity (UIBC).
Additional Information
UIBC (Unsaturated Iron Binding Capacity) Reagent - Safety Data Sheet
UIBC (Unsaturated Iron Binding Capacity) Reagent - Instructions for Use
