OSR6152 Olympus TRF (Transferrin) Reagent, 4 x 7 mL & 4 x 8 mL

Specifications

Manufacturer: Beckman Coulter
Country of Origin: Ireland
Application: Reagent
Number of Tests: 4 x 330
Test Name: Transferrin
Test Type: Anemia / Specific Protein Test
UNSPSC Code: 41116004

Intended Use

System reagent for the quantitative determination of Transferrin in human serum on Beckman Coulter AU analyzers.

About TRF (Transferrin) Reagent

Iron in plasma is bound to the transport protein transferrin. Transferrin is responsible for 50% to 70% of the iron binding capacity of serum.

Transferrin has two iron-binding sites and is largely, but not exclusively, synthesized by the liver.

Transferrin levels rise with iron deficiency and fall in cases of iron overload. An increase in transferrin is seen in iron deficiency anemia. It may also be increased late in pregnancy and in women on oral contraceptives. It is decreased in conditions associated with increased protein loss, such as nephrotic syndrome, chronic renal failure, severe burns, and protein-deficiency states and in severe liver disease. Transferrin is a negative acute-phase protein and will be decreased during any inflammatory state or severe illness.

Methodology

Immune complexes formed in solution scatter light in proportion to their size, shape and concentration. Turbidimeters measure the reduction of incident light due to reflection, absorption, or scatter.

In the procedure, the measurement of the decrease in light transmitted (increase in absorbance) through particles suspended in solution as a result of complexes formed during the antigen-antibody reaction, is the basis of this assay. 

Additional Information 

​  TRF (Transferrin) Reagent - Safety Data Sheet 
​  TRF (Transferrin) Reagent- Instructions for Use